ontology-constrained

LLM Agent With Ontology Constraints Automates Standardization of Legacy Biomedical Metadata

Researchers have developed an LLM-based metadata standardization system that queries standard reporting guidelines and biomedical terminology services in real time. Tested on 839 legacy records from the Human BioMolecular Atlas Program, the approach consistently improves prediction accuracy over LLM-only methods for both ontology-constrained and non-ontology-constrained fields.