medical image classifiers

Input-Dependent Fisher Information Enables Local Sensitivity Analysis of Medical Image Classifiers

A research paper introduces a local sensitivity analysis framework based on the input-dependent Fisher Information Matrix (iFIM) for medical image classifiers. The method projects input images into high- and low-sensitivity components, showing that high-sensitivity components are more strongly tied to predictive confidence and classification performance. This provides a principled tool for interpreting black-box deep neural networks in medical imaging.